About UConn Structural Biology
The UConn Partnership for Excellence in Structural Biology brings together faculty, staff, and students to form an interactive research and training environment. We have active research programs in the structural analysis of macromolecular assemblies and membrane proteins, computational and experimental methods development, computational modeling, and analysis. Our major facilities include NMR, X-ray crystallography, Proteomics & Metabolomics core facilities as well as the National Center for Analytical Ultracentrifugation. The partnership supports collaborative research projects, interdepartmental graduate training and an annual symposium (NESS).
Upcoming Events
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Apr
19
Special Seminar with Dr. Jinghui Zhang 10:30am
Special Seminar with Dr. Jinghui Zhang
Friday, April 19th, 2024
10:30 AM - 11:30 PM
BPB 201
Dr. Jinghui Zang
St. Jude Endowed Chair in Bioinformatics, St. Jude Children’s Research Hospital, Memphis, Tennessee
UConn ’94Co-sponsored by Dept. Molecular and Cell Biology, The Institute for Systems Genomics, and the School of Computing
Genomic Variants in Pediatric Cancer: Driver Discovery, Clinical Testing and Computational Analysis
Jinghui Zhang’s research focuses on developing and applying genomic-based approaches for improving the treatment and outcome of pediatric cancer. Her research on innovative computational methods development has greatly advanced discovery, interpretation, and visualization of somatic and germline variants. She has built a new Computational Biology Department at St Jude by recruiting and mentoring multi-disciplinary computational experts to establish innovative research programs focusing on pediatric cancer. An advocate for genomic data sharing, Zhang initiated the development of St. Jude Cloud, the world’s largest pediatric cancer data sharing platform. She received a PhD in Genetics from the University of Connecticut in 1994 for research done with the late Claire M. Berg (MCB). She continued work at the NCBI for many years, worked in industry (Glaxo Wellcome, Celera Genomics) and at the National Cancer Institute. Since 2010 she has been at the St. Jude Children’s Research Hospital in Memphis. She is an elected fellow of the International Society for Computational Biology.
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Apr
19
MCB Research in Progress: Heyer-Gray 12:20pm
MCB Research in Progress: Heyer-Gray
Friday, April 19th, 2024
12:20 PM
Biology/Physics Building
Helena Heyer-Gray, Klassen Lab
Abaecin-2 modulates interactions in a fungus-growing ant symbiosis by changing copper availability
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Apr
22
Molecular Biology and Biochemistry Work in Progress Talk: Angela Power (Dr. W. Mok Lab) 12:00pm
Molecular Biology and Biochemistry Work in Progress Talk: Angela Power (Dr. W. Mok Lab)
Monday, April 22nd, 2024
12:00 PM - 01:00 PM
Room E2036 & Webex
“Scratching the surface: solidifying substrates used for Staphylococcus aureus biofilm cultivation impact extracellular matrix composition and antibiotic tolerance”
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Apr
23
MCB Seminar Series: Dr. Aoife Heaslip, Tenure Talk 3:30pm
MCB Seminar Series: Dr. Aoife Heaslip, Tenure Talk
Tuesday, April 23rd, 2024
03:30 PM
BPB 131
Dr. Aoife Heaslip, Assistant Professor, Department of Molecular and Cell Biology, University of Connecticut
Host: Carol Teschke
Intracellular cargo transport in Toxoplasma gondii
The human pathogen Toxoplasma gondii (T. gondii) causes life-threatening disease in immunocompromised individuals and when infection occurs in utero. Survival and disease pathogenesis are dependent on host cell invasion, intracellular replication and egress, which results in destruction of the infected cells. In order to complete this lytic cycle, Toxoplasma must traffic proteins to three distinct secretory organelles, the micronemes, rhoptries and dense granules. In this talk I will present our recent work characterizing how actin and an unconventional myosin motor, MyoF regulate protein trafficking and vesicle transport in Toxoplasma.
Bio: Aoife Heaslip received her bachelor’s degree from University College Dublin and PhD degree from the University of Vermont under the mentorship of Dr. Gary Ward. Aoife then moved to Indiana University and worked as a postdoctoral associate with Dr. Ke Hu. She then returned to Vermont to complete a second postdoc with Dr. David Warshaw, an expert in myosin biophysics. I joined the MCB department as an assistant professor in 2017.
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Apr
24
MCB Dissertation Defense: Lorraine Burdick 10:00am
MCB Dissertation Defense: Lorraine Burdick
Wednesday, April 24th, 2024
10:00 AM
BPB 131
Department of Molecular and Cell Biology
University of Connecticut
Announces the
Oral Dissertation Defense for the Doctoral Degree
Lorraine Burdick
B.S. University of Connecticut
Investigating the Developmental Fate of Fibro-Adipogenic Progenitors in Mouse Models of Fibrodysplasia Ossificans Progressiva
Wednesday, April 24, 2024
10:00 AM
BPB 131
Webex Link: https://uconn-cmr.webex.com/meet/lna09001
Major Advisor: David Goldhamer
Associate Advisor: Charles Giardina
Associate Advisor: Leighton Core
Examiner: Lawrence Silbart
Examiner: Caroline Dealy
Link to Current Draft of Dissertation
https://docs.google.com/document/d/11Cb4h7YolwT3UbVc4Um7_yzmNh9aMCT0zxS7b0y74Qc/edit?usp=sharing
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Contact Us
Phone: | (860) 486-4353 |
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E-mail: | victoria.robinson@uconn.edu |
Address: | University of Connecticut Department of Molecular & Cell Biology 91 North Eagleville Road, Unit 3125 Biology/Physics Building 204 Storrs, CT 06269-3125 |